This week in the Product Spotlight: "A New Disulfide-Rich Peptide Toxin, Enterotoxin STh"

A New Disulfide-Rich Peptide Toxin

 

Enterotoxin STh

As mentioned in our current PepTalk, there appears to be a strong implication between Multiple Sclerosis and a toxin produced by C. perfringens bacteria, primarily found in sheep. Many peptide toxins contain several disulfide bonds and can be tricky to synthesize. As experts in synthesizing peptides with multiple disulfide bonds, we are pleased to introduce a new peptide toxin, Enterotoxin STh. Enterotoxigenic E. coli are able to produce several toxic peptides which may cause acute diarrhea in humans and domestic animals. The E. coli heat-stable enterotoxin STh is composed of 19 amino acids containing three intramolecular disulfide bonds, which seem to be important for the correct conformation of the biologically active structure.

Enterotoxin STh
H-Asn-Ser-Ser-Asn-Tyr-Cys-Cys-Glu-Leu-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH
Disulfide Bonds: C6-C11, C7-C15, C10-C18
ENT-3981-PI

We also carry the related toxin:

Enterotoxin STp
ENT-3744-PI

View the rest of our peptides in our toxin collection here.

If a toxin of interest is not commercially available, we can also custom synthesize one for you. Please contact us today for a consultation or quote.