A Systems Pharmacology-Based Approach to Identify Novel Kv1.3 Channel-Dependent Mechanisms in Microglial Activation
Kv1.3 potassium channels regulate microglial functions and are overexpressed in neuroinflammatory diseases. Kv1.3 blockade may selectively inhibit pro-inflammatory microglia in neurological diseases but the molecular and cellular mechanisms regulated by Kv1.3 channels are poorly defined.
Authors from Peptides International
A Unique Peptide with Optimal Nav1.7 Properties for Pain ManagementA look at a just-published open access article, coauthored by this blog post writer.
A Database of Potassium Channel Toxins from Scorpion VenomA resource for researchers of potassium channel blocking toxins
Nav-igating the ChannelsA navigational map to the voltage-gated sodium channels (VGSCor Navs), their sub-types and some of the toxins that block them, including Peptides International's latest release, GpTX-1.