α-Defensin-5 (Human) (0.1mg vial)

  • Product Code: PDF-4415-s
  • Synonyms/Product Alternate Names: Ala-Thr-Cys-Tyr-Cys-Arg-Thr-Gly-Arg-Cys-Ala-Thr-Arg-Glu-Ser-Leu-Ser-Gly-Val-Cys-Glu-Ile-Ser-Gly-Arg-Leu-Tyr-Arg-Leu-Cys-Cys-Arg, HD-5, Human Defensin-5, alpha-Defensin-5, DEFA5
  • Antimicrobial Peptide in Paneth Cells
  • Storage Conditions: -20 °C
  • Molecular Weight: 3582.1
  • Molecular Formula: C144H238N50O45S6
  • Disulfide Bonds: (Disulfide bonds between Cys3-Cys31, Cys5-Cys20, and Cys10-Cys30)
  • One-Letter Code:
    H-ATCYCRTGRCATRESLSGVCEISGRLYRLCCR-OH
  • T. Ganz, M.E. Selsted, D. Szklarek, S.S.L. Harwig, K. Daher, D.F. Bainton, and R.I. Lehrer, J. Clin. Invest., 76, 1427 (1985). (Original; Isolation of HNP 1-3

  • M.E. Selsted, S.S.L. Harwig, T. Ganz, J.W. Schilling, and R.I. Lehrer, J. Clin. Invest., 76, 1436 (1985). (Original; Structure of HNP 1-3

  • X.-M. Fang, Q. Shu, Q.-X. Chen, M. Book, H.-G. Sahl, A. Hoeft, and F. Stuber, Eur. J. Clin. Invest., 33, 82 (2003). (Histochem.; Regulation of Expression

  • R.I. Lehrer and T. Ganz, Ann. N.Y. Acad. Sci., 797, 228 (1996). (Review)

  • E. Martin Porter, M.A. Poles, J.S. Lee, J. Naitoh, C.L. Bevins, amd T. Ganz, FEBS Lett., 434, 272 (1998). (Endogenous Form

  • N.H. Salzman, D. Ghosh, K.M. Huttner, Y. Paterson, and C.L. Bevins, Nature, 422, 522 (2003). (Pharmacol.) 

  • P. Kelly, R. Feakins, P. Domizio, J. Murphy, C. Bevins, J. Wilson, G. Mcphail, R. Poulsom, and W. Dhaliwal, Clin. Exp. Immunol., 135, 303 (2004). (Histochem.; Location in AIDS Patients)

  • F.T. Lundy, D.F. Orr, J.R. Gallagher, P. Maxwell, C. Shaw, S.S. Napier, C.G. Cowan, P.-J. Lamey, and J.J. Marley, Oral Oncol., 40, 139 (2004). (Pharmacol.; Role in Tumor Invasion)

  • L. Zhang, W. Yu, T. He, J. Yu, R.E. Caffrey, E.A. Dalmasso, S. Fu, T. Pham, J. Mei, J.J. Ho, W. Zhang, P. Lopez, and D.D. Ho, Science, 298, 995 (2002)(Pharmacol.; Anti-HIV-1 Activity)

  • R.N. Cunliffe, Mol. Immunol., 40, 463 (2003). (Histochem.; a-Defensin in Gastrointestinal Tract) D.E. Jones and C.L. Bevins, J. Biol. Chem., 267, 23216 (1992). (Original)

  • 1ea
  • $284.00