Cryptdin-4 (Mouse) (0.1 mg vial)

  • Product Code: PDF-4504-s
  • Synonyms/Product Alternate Names: Crp4; Gly-Leu-Leu-Cys-Tyr-Cys-Arg-Lys-Gly-His-Cys-Lys-Arg-Gly-Glu-Arg-Val-Arg-Gly-Thr-Cys-Gly-Ile-Arg-Phe-Leu-Tyr-Cys-Cys-Pro-Arg-Arg
  • Antimicrobial Peptide in Paneth Cells
  • The most potent microbicidal of the mouse Paneth cell α-defensins and is degraded by MMP-7.

  • Storage Conditions: -20 °C
  • Molecular Weight: 755.5
  • Molecular Formula: C158H257N57O38S6
  • Disulfide Bonds: Bonds Between Cys4-Cys29, Cys6-Cys21, Cys11-Cys28
  • CAS Number: 610309-90-5
  • M.E. Selsted, S.I. Miller, A.H. Henschen, and A.J. Ouellette, J. Cell Biol., 118, 929 (1992). (Original)

  • A.J. Ouellette, M.M. Hsieh, M.T. Nosek, D.F. Cano-Gauci, K.M. Huttner, R.N. Buick, and M.E. Selsted, Infect.Immun., 62, 5040 (1994). (Original)

  • A.J. Ouellette, D. Darmoul, D. Tran, K.M. Huttner, J. Yuan, and M.E. Selsted, Infect.Immun., 67, 6643 (1999). (Chem. Synthesis & Pharmacol.)

  • W. Jing, H.N. Hunter, H. Tanabe, A.J. Ouellette, and H.J. Vogel, Biochemistry, 43, 15759 (2004). (Solution Structure : NMR)

  • K. Masuda, N. Sakai, K. Nakamura, S. Yoshioka, and T. Ayabe, J. Innate Immun., 3, 315 (2011). (Pharmacol.)

  • E. Hayase, D. Hashimoto, K. Nakamura, C. Noizat, R. Ogasawara, S. Takahashi, H. Ohigashi, Y. Yokoi, R. Sugimoto, S. Matsuoka, T. Ara, E. Yokoyama, T. Yamakawa, K. Ebata, T. Kondo, R. Hiramine, T. Aizawa, Y.Ogura, T. Hayashi, H. Mori, K. Kurokawa, K. Tomizuka, T. Ayabe, and T. Teshima, J. Exp. Med., 214, 3507 (2017). (Pharmacol.)

  • 1ea
  • $220.00