Peptide YY (Dog, Mouse, Porcine, Rat, 3-36)

  • Acetate salt
  • Product Code: PYY-3726-PI
  • Synonyms/Product Alternate Names: H-Ala-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Ser-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2
  • PYY (3-36), a Y2 receptor agonist, is released from the body's gastrointestinal tract in proportion to caloric intake. It has been shown that peripheral injection of PYY (3-36) in rats inhibited food intake and reduced weight gain. In addition, infusion of PYY (3-36) in humans significantly decreased appetite and reduced food intake by 33% over 24h, which suggests that PYY (3-36) has a role in 'longer term' regulation of food intake. Thus, the PYY (3-36) may represent a lead compound for the development of drugs for the treatment of obesity.

  • Storage Conditions: -20C
  • Molecular Weight: 3980.45
  • Molecular Formula: C176H272N52O54
  • CAS Number: [126339-09-1]
  • One-Letter Code:
    H-AKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY-NH2
  • R.L.Batterham et al., N. Engl. J. Med., 349, 941 (2003).

  • I.G.Halatchev and R.D.Cone, Cell Metab., 1, 159 (2005)

  • PK Chelikani, et al, Am. J Phyiol Regul Integr Comp Physiol,, 293, R39, (2007).

  • G.H.Ballantyne, Obes. Surg., 16, 651 (2006).

  • C.Acuna-Goycolea and A.N.van den Pol, J. Neurosci., 25, 10510 (2005).

  • Y.Shechter et al., FEBS Lett., 579, 2439 (2005).

  • R.L.Batterham et al., Nature, 418, 650 (2002).

  • D.Grandt et al., Regul. Peptides, 40, 161 (1992).

  • 1mg
  • $260.00
  • 5mg
  • $1,040.00