K-252A

  • Product Code: INK-3026-PI
  • Kinase Inhibitor (Pan Specific); Induces Apoptosis and Is Cell Permeable
  • K252a is a potent pan-specific protein kinase inhibitor: PKA (Ki = 18 nM), PKC (Ki = 25 nM) PKG (Ki = 20 nM)1. K252a inhibits CaMK (Ki = 1.8 nM) and phosphorylase kinase (IC50 = 1.7 nM) as well as other kinases. Induces apoptosis and is cell permeable.

    Solubility: Soluble in DMSO (up to 100 mg/ml).

  • Origin: Fermentation product from Nocardiopsis sp.
  • Storage Conditions: -20 ℃
  • Molecular Weight: 467.49
  • Molecular Formula: C27H21N3O5
  • CAS Number: 99533-80-9
  • Kase, et al., Biochem. Biophys. Res. Commun., 142, 436 (1987).

  • Hashimoto, et al., Biophys. Res. Commun., 181, 423 (1991).

  • Berg, et al., J. Biol. Chem., 267, 13 (1992).

  • Ruegg, et al., Trends Pharmacol. Sci., 10, 218 (1989).

  • Mohri, et al., Cancer Invest., 17, 391 (1999).

  • 1mg
  • $140.00
  • 5mg
  • $560.00
  • 25mg
  • $2,240.00