Leuprolide Human

  • Product Code: HOR-260
  • Synonyms/Product Alternate Names: pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt, Leuprorelin
  • A gonadotropin-releasing hormone agonist (GnRH agonist)/LH-RH agonist
  • Leuprorelin (INN) or leuprolide acetate (USAN) is a gonadotropin-releasing hormone agonist (GnRH/LH-RH agonist). By causing constant stimulation of the pituitaryGnRH receptors, it initially causes stimulation (flare), but thereafter decreases pituitary secretion (downregulation) of gonadotropins luteinizing hormone(LH) and follicle-stimulating hormone(FSH). Like other GnRH agonists, leuprolide may be used in the treatment of hormone-responsive cancers such as prostate canceror breast cancer, estrogen-dependent conditions (such as endometriosisor uterine fibroids), to treat precocious puberty, and to control ovarian stimulation in IVF.

    Description: Leuprolide Human Synthetic is a single, non-glycosylated, polypeptide chain containing 9 amino acids and having a molecular mass of 1209 Dalton. The molecular formula is C59H84N16O12.

    Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.

    Formulation: The Leuprorelin was lyophilized from a concentrated (1mg/ml) solution with no additives.

    Solubility: It is recommended to reconstitute the lyophilized Leuprolide in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

    Stability: Lyophilized Leoprolide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Leuprorelin should be stored at 4°C between 2-7 days and for future use below -18°C.
    For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA).
    Please prevent freeze-thaw cycles.

  • Storage Conditions: -20 °C
  • Molecular Formula: C59H84N16O12
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All quantities are subject to availability. Please allow 7-10 days for delivery.

  • 5mg
  • $55.00
  • 25mg
  • $220.00
  • 100mg
  • $650.00