OxymaPure®

  • Product Code: OXY-1050-PI
  • Synonyms/Product Alternate Names: Ethyl (Hydroxyimino)Cyanoacetate, Ethyl Cyano(Hydroxyimino)Acetate, Ethyl Cyanoglyoxalate-2-Oxime, Ethyl Isonitrosocyanoacetate, ethyl-2- Cyano-2-(Hydroxyimino)-Acetate
  • Considered as a replacement for HOBt , HOAT , HOOBt, HOPO , Cl-HOBT and other analogues
  • An ideal additive used with carbodiimide coupling methodology for amide bond formation.  The 2-cyano-2-(hydroxyimino)acetate displays a remarkable capacity to suppress racemization and an impressive coupling efficiency in both automated and manual synthesis.

    OxymaPure® has a pKa=4.60

    OxymaPure® has been tested for oral toxicity and dermal irritation and was found as non-toxic and non-allergic (Safe (LD50 = 300-2000 mg/kg)). It also has less risk of explosively and flammability than similar products and has no limitation in land, sea and air transportation (low risk of explosion).

  • Storage Conditions: 2-10 °C
  • Purity: ≥99.5%
  • Molecular Weight: 142.12
  • Molecular Formula: C5H6N2O3
  • CAS Number: 3849-21-6
  • J.M. Collins, et al., Org. Lett., 16, 940 (2014).

  • S.N. Khattab, et al., Eur. J. Org. Chem., 3275 (2010).

  • R. Subiros-Funosas, et al., Chem. Eur. J., 15, 9394 (2009).

  • N. Babu Palakurthy, et al., Eur. J. Org. Chem., 2627 (2013).

  • R.Subiros-Funosas, et al.PeptideScience, 98, Vol. 2

  • S.N. Khattab, Bull. Chem. Soc. Jpn., 83, No. 11, 1374 (2010).

  • 25g
  • $29.00
  • 100g
  • $85.00