A New Peptide Drug Is Approved

It is nice to see new FDA-approved peptide-based drugs.  Recently, Synergy Pharmaceuticals received FDA approval for their uroguanylin derivative, TRULANCE™ (plecanatide), in adult patients.  Plecanatide is designed to mimic the function of uroguanylin.  Uroguanylin helps alleviate chronic idiopathic constipation (CIC) by increasing water levels in the gastrointestinal tract.  The drug is also being evaluated for treatment of chronic irritable bowel syndrome.1 Unlike many other peptide drugs, plecanatide is an oral medication.  The market is underserved and rather large with approximately 42 million people having CIC, according to the National Institutes of Health.2

 References:

1.    http://ir.synergypharma.com/press-releases/detail/1831/synergy-pharmaceuticals-trulance-plecanatide and http://www.synergypharma.com/research-and-development/uroguanylin
2.   http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm537725.htm

Industry News , Biologically Active Peptides

Denise Karounos

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Denise Karounos joined Peptides International in October 2016. After completing her BS in chemistry from West Virginia University, she spent time as an organic chemist at Bachem Bioscience synthesizing peptides and amino acid derivatives. Denise has experience with both solid and solution-phase peptide synthesis, and has worked under both research and cGMP settings. After completing her MBA from Saint Joseph’s University, Denise transitioned into product management of peptides and amino acid derivatives. In her marketing role, she had many duties including but not limited to product management, market research, creating and producing marketing materials, handling US catalog distribution and customer database, email marketing, quoting and inside sales, sales calls, and coordinating and attending trade conferences. 

At PI, Denise's duties encompass both sales and marketing, bringing to bear her extensive lab and sales support experience. Contact her today and see how Denise can assist you with your peptide research project.