Yet Another Function for Neuromedins?

The Neuromedins are a diverse family of neuropeptides and are G protein-coupled receptor (GPCR) ligands. They control a variety of functions such as vasoconstriction, hormonal regulation, smooth muscle contraction, feeding regulation, nociceptive pain, stress regulation, and play a possible role in tumor suppression.

In our related Product Spotlight from the PEPNET newsletter, Vol. 31 issue 4, we showcased three recently released Neuromedin items. By happenstance, there is also a new paper that highlights an aspect of the feeding-regulation characteristics found in this class of peptides in conjunction with the most common eating disorder.   In the journal Nutrients, authors from the Hommel laboratory within the Center for Addiction Research which is affiliated with the University of Texas, correlated binge-type eating in rats with synaptosomal NMUR2 (G protein-coupled receptor Neuromedin U Receptor 2) protein expression in the NAc (nucleus accumbens) and the VTA (ventral tegmental area) of rats.

Depending on the ratio of fat to carbohydrates, synaptosomal NMUR2 protein in the NAc or in the VTA demonstrated opposing results. The article is open access and can found through the link below.

In addition, here are our three most recent Neuromedins:          

Reference

  1. A.E. Smith, J.M. Kasper, N.C. Anastasio, and J.D. Hommel, Nutrients, 11(2), 327 (2019). https://doi.org/10.3390/nu11020327

 Thanks to Denise Karounos and Dr. Satendra S. Chauhan for their assistance with this article.

Industry News , Biologically Active Peptides , Neuroscience

Robert Brousseau

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Robert Brousseau, the Director of Marketing and Catalog Sales Development at Peptides International, has a wide range of responsibilities that include maintaining the Peptides International brand integrity and creating and implementing all materials related to marketing the company's product line. He is also tasked with the catalog portfolio sales.  Since joining the company in 2004, he has incorporated media that now includes printed material such as product brochures and the long-running PEPNET newsletter, along with the company Website, social media, email and other outlets.  Additionally, he assists the staff with IT issues they encounter.  Bob has a background in graphic design, marketing, and advertising, in addition to project management and packaging.  He received his B.A. in Art from the University of Louisville, with additional post-graduate studies in education and design.