C-Peptide Levels Correlate to Pre-Diabetes Risk Among Women with a History of Gestational Diabetes


Gestational diabetes mellitus (GDM) is impaired glucose tolerance in some pregnant women and has been steadily increasing woldwide.1 In addition, GDM affects nearly one in seven pregnancies and leads to a three to seven-fold increase in risk of developing type II diabetes later in life.2 Recently, a team of researchers, led by Ping Yin of the Shanghai Ninth People’s Hospital and Ping Shao of Tianjin Women’s and Children’s Health Center, published findings about a link between the risk of pre-diabetes and diabetes and serum C-Peptide levels in Chinese women who have a history of gestational diabetes. They found a correlation by looking at a cross-sectional study of 1263 Chinese women and using statistical analysis to analyze C-Peptide serum levels. Interestingly, this is independent of body mass index (BMI) and fasting insulin levels, although both BMI and C-Peptide levels are risk factors.3 Future research into C-Peptide levels and its connection to diabetes are certainly warranted.


  1. https://www.idf.org/our-activities/care-prevention/gdm
  2. http://www.diabetesforecast.org/2015/jan-feb/exploring-gestational-diabetes-leads-type-2.html
  3. P. Yin et al., Journal of Diabetes and Its Complications, 0(0), 2017. [Article in print] Retrieved from http://www.jdcjournal.com/article/S1056-8727(17)30953-4/fulltext
Industry News , Biologically Active Peptides , Diabetes

Denise Karounos

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Denise Karounos joined Peptides International in October 2016. After completing her BS in chemistry from West Virginia University, she spent time as an organic chemist at Bachem Bioscience synthesizing peptides and amino acid derivatives. Denise has experience with both solid and solution-phase peptide synthesis, and has worked under both research and cGMP settings. After completing her MBA from Saint Joseph’s University, Denise transitioned into product management of peptides and amino acid derivatives. In her marketing role, she had many duties including but not limited to product management, market research, creating and producing marketing materials, handling US catalog distribution and customer database, email marketing, quoting and inside sales, sales calls, and coordinating and attending trade conferences. 

At PI, Denise's duties encompass both sales and marketing, bringing to bear her extensive lab and sales support experience. Contact her today and see how Denise can assist you with your peptide research project.