Peptides International

  Quick Reference Peptide Toxins


The featured peptide toxins below are produced by the Peptide Institute of Osaka, Japan, and are available in the USA from Peptides International in Louisville, Kentucky.  These peptides represent some of our most popular products.  It is well known that these types of toxins present a synthetic challenge due not only to their chain length but also to the presence of multiple disulfide bridges. These toxins are mainly produced from solution phase strategies, rather than solid phase, to meet the high standards set forth by the experts at the Peptide Institute. Peptides International is proud to offer these peptide toxins to the international research community. These products as well as our other fine products are the highest purity available anywhere in the world.  Please remember at Peptides International we are Passionate about Purity.

CODE

COMPOUND

QTY

USD
PAG-4256-s w -Agatoxin-IVA 0.1 mg vial

335
PAG-4294-s w -Agatoxin TK CAS 145017-83-0 0.1 mg vial

390
PAG-4247-s Agelenin 0.1 mg vial

335
PAP-4257-v Apamin CAS 24345-16-2 0.5 mg vial

195
PCC-4310-s Calcicludine CAS 178037-96-2 0.1 mg vial

309
PCL-4255-s Calciseptine CAS 178805-91-9 0.1 mg vial

335
PCB-4227-s Charybdotoxin (ChTX) CAS 95751-30-7 0.1 mg vial

235
PCN-4282-v Chlorotoxin 0.5 mg vial

563
PCN-4126-v a-Conotoxin GI CAS 76862-65-2 0.5 mg vial

279
PCN-4140-v a-Conotoxin MI CAS 83481-45-2 0.5 mg vial

285
PCN-4311-v a-Conotoxin ImI CAS 156467-85-5 0.5 mg vial

285
PCN-4228-v a-Conotoxin SI CAS 115797-06-03 0.5 mg vial

285
PCN-4263-v µ-Conotoxin GS 0.5 mg vial

419
PCN-4217-v µ-Conotoxin GIIIB CAS 140678-12-2 0.5 mg vial

409
PCN-4161-v w -Conotoxin GVIA CAS 106375-28-4 0.5 mg vial

397
PCN-4283-s w -Conotoxin MVIIC CAS 147794-23-8 0.1 mg vial

167
PCN-4283-v w -Conotoxin MVIIC CAS 147794-23-8 0.5 mg vial

369
PCN-4289-v w -Conotoxin MVIIA CAS 107452-89-1 0.5 mg vial

329
PCN-4284-v w -Conotoxin SVIB CAS 150433-82-2 0.5 mg vial

329
PDN-4330-s Dendrotoxin I CAS 129203-60-7 0.1 mg vial

315
PGX-4433-s Guangxitoxin-1E (GxTX-1E) 0.1 mg vial

229
PIB-4235-s Iberiotoxin (IbTX) CAS 129203-60-7 0.1 mg vial

239
PIM-4343-s Imperatoxin A (IpTXa) CAS 172451-37-5 0.1 mg vial

235
PKL-4259-s Kaliotoxin (1-37) CAS 145199-73-1 0.1 mg vial

259
PAR-4290-s Margatoxin (MGTX) CAS 145808-47-5 0.1 mg vial

235
PMC-4258-v Mast Cell Degranulating Peptide
CAS 32908-73-9		 0.5 mg vial

279
PMS-4107-v Mastoparan CAS 72093-21-1 0.5 mg vial

65
PMT-4341-s Muscarinic Toxin 1 (MTX1, MT1) 0.1 mg vial

315
PMT-4340-s Muscarinic Toxin 7 (MTX7, MT7) 0.1 mg vial

315
PNT-4195-s Neurotoxin, NSTX-3 CAS 69344-74-7 0.1 mg vial

99
PPL-4300-s PLTX-II 0.1 mg vial

395
PSF-4206-s Sarafotoxin S6b CAS 116303-65-2 0.1 mg vial

159
PSF-4246-s Sarafotoxin S6c CAS 121695-87-2 0.1 mg vial

159
PSC-4260-s Scyllatoxin/Leiurotoxin 0.1 mg vial

229
PCB-4363-s SNX-482

0.1 mg vial

330
PSK-4287-s Stichodactyla Toxin

0.1 mg vial

239
PTK-4364-s Tertiapin 0.1 mg vial

159
PTT-4313-s Tityustoxin Ka 0.1 mg vial

315

*All -s and -v products are sold as net peptide weight. Some products are available in bulk quantities, please inquire.
Conotoxin peptides are not available for export without a license from the US Department of Commerce. 
To place an order for conotoxin peptides to be shipped within the United States please contact
Peptides International to obtain important information regarding the CDC Select Agent Transfer Program . 
Thank you for your cooperation!

Specific Channel Type

Channel Blocker

Effective Concentration

Notes

P-type

w -Agatoxin TK

IC50 = 15 nM

 Also blocks a Q-type-like Ca2+ channel in rat hippocampal neurons with low sensitivity

w -Agatoxin IVA

Kd = 2 nM

 Selective blocker with high affinity

 

N-type

w -Conotoxin GVIA,

100 nM - 2 m M

 Reversibly blocks synapse neurotransmitter release.

w -Conotoxin MVIIA

100 nM - 1 m M

 Highly potent blocker, competes with w -Conotoxin GVIA

w -Conotoxin SVIB

100 nM - 2 m M

 Pre-synaptic blocker.

L-type

Calciseptine

100 nM - 2 m M

 Very specific and highly potent.

Calcicludine

L-type: IC50 = 200 pM

 Also blocks N- and P-types to a lesser extent

P/Q-type

w -Conotoxin MVIIC

50 nM - 1 m M

 Selective and highly potent

R-type

SNX-482

IC50 = 15 - 30 nM

 Specific for Class E subtype

PLTX-II

 Pre-synaptic blocker.

 

TYPE

CODE

COMPOUND

QTY

USD
Ca2+ Channel Blockers
L-type PCL-4255-s Calciseptine 0.1 mg vial 335
L-type PCC-4310-s Calcicludine (CaC) 0.1 mg vial 309
N-type PCN-4161-v w -Conotoxin GVIA 0.5 mg vial 397
N-type PCN-4289-v w -Conotoxin MVIIA 0.5 mg vial 329
N-type PCN-4284-v w -Conotoxin SVIB 0.5 mg vial 329
P-type PAG-4256-s w -Agatoxin IVA 0.1 mg vial 335
P-type PAG-4294-s w -Agatoxin TK 0.1 mg vial 390
P/Q-type PCN-4283-s w -Conotoxin MVIIC 0.1 mg vial 167
P/Q-type PCN-4283-v w -Conotoxin MVIIC 0.5 mg vial 369
R-type PCB-4363-s SNX-482 0.1 mg vial 330
PPL-4300-s PLTX-II 0.1 mg vial 395
K+ Channel Blocker
Ca2+ Activated K+ Channel Blockers
BK-type1 PIB-4235-s Iberiotoxin (IbTX) 0.1 mg vial 239
BK-type1 PKL-4259-s Kaliotoxin (1-37) 0.1 mg vial 259
IK-type2 PCB-4227-s Charybdotoxin* (ChTX) 0.1 mg vial 235
SK-type3 PAP-4257-v Apamin 0.5 mg vial 195
SK-type3 PSC-4260-s Scyllatoxin (Leiurotoxin I) 0.1 mg vial 229
1 High Conductance; 2 Intermediate Conductance; 3 Small Conductance *also has BK-type blocking activity
Voltage Dependent K+ Channel Blockers
PMC-4258-v Mast Cell Degranulating (MCD) Peptide 0.5 mg vial 279
PSK-4287-s Stichodactyla Toxin (ShK) 0.1 mg vial 239
PAR-4290-s Margatoxin (MgTX) 0.1 mg vial 235
PTT-4313-s Tityustoxin Ka (TsTX-K ) 0.1 mg vial 315
PDN-4330-s Dendrotoxin I 0.1 mg vial 315
Na+ Channel Blockers
PCN-4217-v µ-Conotoxin GIIIB 0.5 mg vial 409
PCN-4263-v µ-Conotoxin GS 0.5 mg vial 419
Cl- Channel Blocker
PCN-4282-v Chlorotoxin 0.5 mg vial 563

To Order Contact
Peptides International Inc.
11621 Electron Drive
Louisville, Kentucky 40299

Call 800-777-4779 (USA and Canada) or 502-266-8787
Fax 502-267-1FAX (1329) or E-mail: peptides@pepnet.com

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