A Few "Classic" References in Combinatorial
Chemistry
- Use of peptide synthesis to probe viral antigens for
epitopes to a resolution of a single amino acid,"
H.M. Geysen, R.H. Meloen, and S.J. Barteling, Proc. Natl.
Acad. Sci., USA, 81, 3998-4002 (1984).
- "General method for the rapid solid-phase synthesis
of large numbers of peptides: Specificity of
antigen-antibody interactions at the level of individual
amino acids," R.A. Houghten, Proc. Natl. Acad. Sci.,
USA, 82, 5131-5135 (1985).
- "General method for rapid synthesis of
multicomponent peptide mixtures", A. Furka, F.
Sebestyen, M. Asgedom, and G. Dibo, Int. J. Peptide
Protein Res., 37, 487-493 (1991).
- "A new type of synthetic peptide library for
identifying ligand-binding activity", K.S. Lam, S.E.
Salmon, E.M. Hersh, V.J. Hruby, W.M. Kazmierski, and R.J.
Knapp, Nature, 354, 82-84 (1991).
- "Generation and use of synthetic peptide
combinatorial libraries for basic research and drug
discovery", R.A. Houghten, C. Pinilla, S.E.
Blondelle, J.R. Appel, C.T. Dooley, and J.H. Cuervo,
Nature, 354, 84-86 (1991).
- "Light-directed, spatially addressable parallel
chemical synthesis", S. Fodor, J.L. Read, M.C.
Pirrung, L. Stryer, A.T. Lu, and D. Solus, Science, 251,
767-773 (1991).
- "Diversomers: An approach to nonpeptide,
non-oligomeric chemical diversity", S. Hobbs Dewitt,
J.S. Kiely, C.J. Stankovic, M.C. Schroeder, D.M.R. Cody,
and M.R. Pavia, Proc. Natl. Acad. Sci., USA, 90,
6909-6913 (1993).
- "The combinatorial synthesis and chemical and
biological evaluation of a 1,4-benzodiazepine
library", B.A. Bunin, M.J. Plunkett, and J.A.
Ellman, Proc. Natl. Acad Sci., USA, 91, 4708-4712 (1994).
