Quick Reference Caspase Related Products
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Quick Reference Caspase Related Products |
| Code | Substrates |
Quantity | Price (USD) |
| MCA-3198-v | Ac-Leu-Glu-His-Asp-MCA [Ac-LEHD-MCA] Substrate for Caspase 9 |
5 mg vial |
108 |
| MCA-3195-v | Ac-Ile-Glu-Thr-Asp-MCA [Ac-IETD-MCA] Acetyl-L-Isoleucyl-L-Glutamyl-L-Threonyl-Aspartic Acid a-(4-Methyl-Coumaryl-7-Amide) (M.W. 675.69) C31H41N5O12 Substrate for Procaspase 3 Cleaving Enzyme (Caspase-8/ Caspase-6/ Granzyme-B) |
5 mg vial |
108 |
| MCA-3185-v | Ac-Lys-Thr-Lys-Gln-Leu-Arg-MCA [Ac-KTKQLR-MCA] Acetyl-L-Lysyl-L-Threonyl-L-Lysyl-L-Glutaminyl-L-Leucyl-L-Arginine a-4-Methyl-Coumaryl-7-Amide (M.W. 972.15) C45H73N13O11 Substrate for Hepatocyte Growth Factor-Activator (HGF-A) |
5 mg vial | 129 |
| MCA-3186-v | Ac-Trp-Glu-His-Asp-MCA [Ac-WEHD-MCA] Acetyl-L-Tryptophyl-L-Glutamyl-L-Histidyl-L-Aspartic Acid a-(4-Methyl-Coumaryl-7-Amide) (M.W. 784.78) C38H40N8O11 Substrate for Caspase-1 (ICE), Caspase-4 and Caspase-5 |
5 mg vial | 108 |
| MCA-3161-v | Ac-Tyr-Val-Ala-Asp-MCA [Ac-YVAD-MCA] Acetyl-L-Tyrosyl-L-Valyl-L-Alanyl-L-Aspartic Acid a-(4-Methyl-Coumaryl-7-Amide) (M.W. 665.70) C33H39N5O10 Substrate for ICE (IL-1 -Converting Enzyme) |
5 mg vial | 82 |
| MOC-3183-v | MOCAc-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-NH2 [MOCAc-YVADAPK(Dnp)-NH2] (7-Methoxycoumarin-4-yl)acetyl-L-Tyrosyl-L-Valyl-L-Alanyl-L-Aspartyl- L-Alanyl-L-Prolyl-Ne-(2,4-Dinitrophenyl)-L-Lysine Amide (M.W. 1144.2) C53H65N11O18 Fluorescence-Quenching Substrate for Caspase-1 (ICE) |
1 mg vial |
163 |
| MOC-3184-v | MOCAc-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-NH2 [MOCAc-DEVDAPK(Dnp)-NH2] (7-Methoxycoumarin-4-yl)acetyl-L-Aspartyl-L-Glutamyl-L-Valyl-L-Aspartyl- L-Alanyl-L-Prolyl-L-Ne -(2,4-Dinitrophenyl)-L-Lysine Amide (M.W. 1154.1) C50H63N11O21 Fluorescence-Quenching Substrate for Caspase-3 (Cpp32, Yama, Apopain) |
1 mg vial |
163 |
| SAP-3171-v | Ac-Asp-Glu-Val-Asp-MCA [Ac-DEVD-MCA] Acetyl-L-Aspartyl-L-Glutamyl-L-Valyl-L-Aspartic Acid a-(4-Methyl-Coumaryl-7-Amide) (M.W. 675.65) C30H37N5O13 Substrate for Apopain |
5 mg vial |
77 |
| Code | Caspase Inhibitors |
Quantity | Price (USD) |
| ICA-3199-v | Ac-Leu-Glu-His-Asp-H (aldehyde) [Ac-LEHD-H] Acetyl-L-Leucyl-L-Glutamyl-L-Histidyl-L-Aspart-1-al Inhibitor for Caspase 9 |
5 mg vial |
250 |
| ICA-3192-v | Ac-Asp-Met-Gln-Asp-H (aldehyde) [Ac-DMQD-H] Acetyl-L-Aspartyl-L-Methionyl-L-Glutaminyl-L-Aspart-1-al (M.W. 533.56) C20H31N5O10S Inhibitor for Caspase-3 |
5 mg vial |
300 |
| ICA-3196-v | Ac-Ile-Glu-Thr-Asp-H (aldehyde) [Ac-IETD-H] Acetyl-L-Isoleucyl-L-Glutamyl-L-Threonyl-L-Aspart-1-al (M.W. 502.52) C21H34N4O10 Inhibitor for Caspase-8/Caspase-6/Granzyme-B |
5 mg vial |
200 |
| ICA-3182-v | Ac-Val-Glu-Ile-Asp-H (aldehyde) [Ac-VEID-H] Acetyl-L-Valyl-L-Glutamyl-L-Isoleucyl-L-Aspart-1-al (M.W. 500.55) C22H36N4O9 Inhibitor for Caspase-6 (Mch2) |
5 mg vial |
218 |
| ICA-3189-v | Z-Glu-Lys(Biotinyl)-Asp-CH2-DMB Carbobenzoxy-L-Glutamyl-L-Ne -Biotinyl-Lysyl-L-Aspart-1-yl-[(2,6-Dimethylbenzoyl)oxy]methane (M.W. 897.02) C43H56N6O13S Affinity Ligand for Caspases |
1 mg vial |
100 |
| ICA-3187-v | Ac-Trp-Glu-His-Asp-H (aldehyde) [Ac-WEHD-H] Acetyl-L-Tryptophyl-L-Glutamyl-L-Histidyl-L-Aspart-1-al (M.W. 611.61) C28H33N7O9 Inhibitor for Caspase-1 (ICE) |
5 mg vial |
200 |
| ICL-3180-v | Ac-Tyr-Val-Ala-Asp-CH2Cl [Ac-YVAD-CH2Cl] Acetyl-L-Tyrosyl-L-Valyl-L-Alanyl-L-Aspart-1-yl- Chloromethane (M.W. 541.00) C24H33N4O8Cl Inhibitor for Caspase-1 (ICE) |
5 mg vial |
200 |
| IAT-3165-v | Ac-Tyr-Val-Ala-Asp-H (aldehyde) [Ac-YVAD-H] Acetyl-L-Tyrosyl-L-Valyl-L-Alanyl-L-Aspart-1-al (M.W. 492.53) C23H32N4O8 Interleukin-1 Converting Enzyme Inhibitor |
5 mg vial |
195 |
| IAT-3166-v | Ac-Tyr-Val-Lys-Asp-H (aldehyde) [Ac-YVKD-H] Acetyl-L-Tyrosyl-L-Valyl-L-Lysyl-L-Aspart-1-al (M.W. 549.62) C26H39N5O8 Interleukin-1 Converting Enzyme Inhibitor Affinity ligand for Interleukin-1 Converting Enzyme |
5 mg vial |
195 |
| IAP-3172-v | Ac-Asp-Glu-Val-Asp-H (aldehyde) [Ac-DEVD-H] Acetyl-L-Aspartyl-L-Glutamyl-L-Valyl-L-Aspart-1-al (M.W. 502.48) C20H30N4O11 Inhibitor for Apopain |
5 mg vial |
195 |
| IBA-3173-v | Biotinyl-Asp-Glu-Val-Asp-H (aldehyde) [Bio-DEVD-H] Biotinyl-L-Aspartyl-L-Glutamyl-L-Valyl-L-Aspart-1-al (M.W. 686.74) C28H42N6O12S Affinity Ligand for Apopain |
1 mg vial |
99 |
| ICE-3174-v | Z-Asp-CH2-DCB Carbobenzoxy-L-Aspartyl-a- [(2,6-Dichlorobenzoyl)oxy]methane (M.W. 454.26) C20H17NO7Cl2 Inhibitor for ICE/ICE-like Proteases |
5 mg vial |
195 |
Human ICE/CED-3 Protease Nomenclature*
| Caspase-1 | =ICE | Caspase-6 | =Mch2 |
| Caspase-2 | =ICH-1 | Caspase-7 | =Mch3, ICE-LAP3, CHM-1 |
| Caspase-3 | =CPP32, Yama, Apopain | Caspase-8 | =MACH, FLICE, Mch5 |
| Caspase-4 | =TX, ICH-2, ICEret-11 | Caspase-9 | =ICE-LAP6, Mch6 |
| Caspase-5 | =ICEret-111, TY | Caspase-10 | Mch4 |
*E.S. Alnemri, et al. Cell, 87, 171 (1996)
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